Basic Fibroblast Growth Factor Inhibits Apoptosis and Promotes Proliferation of Adipose-Derived Mesenchymal Stromal Cells Isolated from Patients with Type 2 Diabetes by Reducing Cellular Oxidative Stress

Figure 4

The morphology of healthy and diabetic-ASCs cultured in the presence or absence of bFGF in 5 ng/mL or 10 ng/mL concentration, evaluated after 7 days of cell propagation. Actin filaments were visualized with atto-594-labelled phalloidin and the nuclei with DAPI. Images included in the graph are representative and show characteristic features of examined cultures. In bFGF-treated cultures, the majority of cells exhibited elongated spindle-shaped morphology with no signs of apoptosis. Magnification: ×100.