Basic Fibroblast Growth Factor Inhibits Apoptosis and Promotes Proliferation of Adipose-Derived Mesenchymal Stromal Cells Isolated from Patients with Type 2 Diabetes by Reducing Cellular Oxidative Stress

Figure 7

Changes in oxidative stress level in diabetic-ASCs after exposition to bFGF in a concentration of 5 ng/mL or 10 ng/mL with reference to nontreated healthy and diabetic-ASC controls. Detection of intracellular ROS along with mitochondria localization via MitoRed stain in investigated cultures by fluorescence microscopy (a). Quantification of extracellular ROS, NO, and SOD levels (b). p value <0.05 and p value <0.001.

(a)

(b)