EGCG Prevents High Fat Diet-Induced Changes in Gut Microbiota, Decreases of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice

Table 1

Body weight and food and water intake of C57BL/6J male mice over a period of 4 months.

Chow intake [g per day]

Water intake [ml per day]

Weight [g]

Month

1

2

3

4

1

2

3

4

1

2

3

4

Intervention

CD

2.64 ± 0.17

2.11 ± 0.62

2.08 ± 0.61

1.99 ± 0.64

5.60 ± 0.99

5.36 ± 0.99

5.40 ± 0.91

5.05 ± 1.27

23.99 ± 1.50

25.92 ± 1.09

26.94 ± 1.42

27.88 ± 1.49

CD + EGCG

2.67 ± 0.12

2.61 ± 0.13

2.63 ± 0.12

2.62 ± 0.28

5.19 ± 0.61

5.13 ± 0.54

4.83 ± 0.65

4.60 ± 0.39

24.16 ± 1.52

25.81 ± 1.32

26.98 ± 1.53

28.43 ± 1.76

HFD

2.56 ± 0.10

2.59 ± 0.15

2.60 ± 0.13

2.56 ± 0.13

5.30 ± 0.43

5.13 ± 0.47

4.97 ± 0.54

5.07 ± 0.39

30.54 ± 3.43

37.62 ± 4.11

42.88 ± 4.58

45.99 ± 4.46

HFD + EGCG

2.57 ± 0.10

2.50 ± 0.10

2.58 ± 0.13

2.55 ± 0.16

5.07 ± 0.61

4.56 ± 0.40

4.43 ± 0.41

4.55 ± 0.31

30.74 ± 3.43

38.79 ± 3.07

44.72 ± 3.68

47.69 ± 3.45