Platelet Carbonic Anhydrase II, a Forgotten Enzyme, May Be Responsible for Aspirin Resistance

Table 2

Comparison of prostanoids and markers of platelet activation in subgroups separated according to ASA response.

—	Decreased ASA response; (mean ± SEM)	Normal ASA response; (mean ± SEM)
N	36–	25–	—
PAI-1 [ng/ml]	3.11 ± 0.31	3.66 ± 0.32	0.04
Sel-P [ng/ml]	37.45 ± 2.10	40.26 ± 3.07	0.56
TxB2 [pg/ml]	1557.8 ± 410.7	826.2 ± 144.6	0.28
6-keto-PGF1α [pg/ml]	215.16 ± 20.77	187.98 ± 18.41	0.40

PAI-1: plasminogen activator inhibitor-1; Sel-P: P-selectin; TxB₂: thromboxane B₂, 6-keto-PGF1α: 6-keto prostaglandin F1α.