Ameliorative Effect of Daidzein on Cisplatin-Induced Nephrotoxicity in Mice via Modulation of Inflammation, Oxidative Stress, and Cell Death

Figure 2

Effect of daidzein on cisplatin-induced renal dysfunction in mice. Cisplatin caused significant renal dysfunction as determined by the levels of NGAL (a), BUN (b), creatinine (c), and urinary KIM-1 at 72 hours (d). Cisplatin induced kidney injury which was attenuated by daidzein treatment. Results are mean ± SEM (/group). versus vehicle and ^# versus cisplatin.

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