MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma

Figure 2

miR-34a target genes regulating the hallmarks of cancer. Eleven targets were investigated in the study. (a) List of targets analyzed by either immunohistochemistry (blue box) or quantitative real-time PCR (yellow box). (b) Classification of the miR-34a target genes and proteins according to their major role in cancer-related biology. They are enrolled in cellular differentiation, proliferation, apoptosis, and angiogenesis.

(a)

(b)