Differential Susceptibility of Germ and Leydig Cells to Cadmium-Mediated Toxicity: Impact on Testis Structure, Adiponectin Levels, and Steroidogenesis
Table 1
Biometric and stereological testicular parameters in control rats and those exposed to cadmium (Cd).
Parameters
CT
Cd1
Cd2
Cd3
Cd4
Testis (g)
1.53 ± 0.09
0.89 ± 0.22
0.83 ± 0.21
1.0 ± 0.11
0.94 ± 0.20
Albuginea (g)
0.07 ± 0.01
0.05 ± 0.01
0.07 ± 0.03
0.1 ± 0.05
0.1 ± 0.07
Tubule (%)
92.9 ± 0.17
88.9 ± 7.5
79.7 ± 11.5
88.5 ± 7.6
85.8 ± 8.4
Intertubule (%)
7.1 ± 0.2
11.1 ± 7.5
20.4 ± 11.5
11.5 ± 7.6
14.2 ± 8.4
Blood vessels (%)
4.6 ± 2.9
5.6 ± 4.9
4.5 ± 2.1
3.4 ± 2.2
2.9 ± 0.7
Lymphatic vessels (%)
46.4 ± 2.6
39.2 ± 20.0
28.5 ± 19.6
54.9 ± 6.9
33.4 ± 22.4
Connective tissue (%)
14.1 ± 5.2
16.2 ± 9.0
47.3 ± 30.0
30.7 ± 32.3
40.3 ± 35.9
Control (CT): 0.9% saline; Cd1: 0.67 mg Cd/kg; Cd2: 0.74 mg Cd/kg; Cd3: 0.86 mg Cd/kg; and Cd4: 1.1 mg Cd/kg. Data are expressed as mean and standard deviation (mean ± SD). Statistical difference ( versus CT).
