Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice
Effects of FMF on Nrf2 nuclear translocation and its target gene expression. (a) Nuclear and cytoplasmic extracts of liver tissues were prepared and protein level of Nrf2 was determined by western blot. Lamin B and tubulin were used as endogenous controls for nucleus and cytoplasm, respectively. (b) Total cellular protein from liver tissues was extracted, and protein levels of Nrf2, NQO1, and HO-1 were determined by western blot. GAPDH was used as an endogenous control. Relative intensity of the immunoreactive bands was analyzed and results are shown as (). , compared with the control group; ### compared with APAP-intoxicated group.
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