Tocotrienol-Rich Fraction Ameliorates Antioxidant Defense Mechanisms and Improves Replicative Senescence-Associated Oxidative Stress in Human Myoblasts

Figure 4

Cellular uptake of vitamin E isomers by myoblasts. (a) Untreated control, TRF- and ATF-treated young, presenescent, and senescent myoblasts. Cellular uptake of 5 vitamin E isomers was significantly higher in TRF-treated myoblasts. (b) NAC-, TRF + NAC-, and ATF + NAC-treated young, presenescent, and senescent myoblasts. Cellular uptake of 5 vitamin E isomers was significantly higher in TRF + NAC-treated myoblasts. Denoting , significantly different compared to the young control, , significantly different compared to the presenescent control, and , significantly different compared to the senescent control. Data are presented as the mean ± SD, .

(a)

(b)