circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis

<div>circRNA_0046367-dependent attenuation of hepatocellular steatosis ameliorates lipid peroxidation and mitochondrial dysfunction. (a), (b) circRNA_0046367 expression correlates to MDA (a) and SOD (b) levels of the steatosis group in negative and positive manner, respectively. (c), (d) circRNA_0046367 treatment reduces the indicator of lipid peroxidation (MDA) (c), whereas increases the antioxidative enzyme (SOD) (d) on a basis of steatosis improvement. (e), (f) Fluorescent assay for MMP represents the alleviated mitochondrial injury (e) (400x), with statistical significance (f), resulting from circRNA_0046367-dependent mitigation of lipid peroxidation. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: circRNA_0046367 Prevents Hepatoxicity of Lipid Peroxidation: An Inhibitory Role against Hepatic Steatosis 