Biotransformation of Dioscorea nipponica by Rat Intestinal Microflora and Cardioprotective Effects of Diosgenin

Figure 2

Base peak chromatograms (BPC) of Dioscorea nipponica (a), control I using intestinal microflora and medium (b), control II using D. nipponica extract and medium (c), D. nipponica extract after biotransformed by intestinal microflora and medium (d) by LC–Q-TOF/MS in negative ion mode (1 protodioscin, 2 protogracillin, 3 pseudoprotodioscin, 4 pseudoprotogracillin, 5 dioscin, 6 gracillin, 7 polyphyllin V, and 8 diosgenin).

(a)

(b)

(c)

(d)