Pharmacological Basis for Use of Armillaria mellea Polysaccharides in Alzheimer’s Disease: Antiapoptosis and Antioxidation
Effect of AMPSc on Aβ clearance in the blood and hippocampus. (a) The levels of Aβ in serum were significantly enhanced by AMPS. Data are expressed as mean ± S.E.M. (). # versus normal mice (CTRL), versus AD mice. AMPS significantly reduced Aβ aggregates in hippocampus of AD mice analyzed via (b) thioflavin-S fluorescence staining (; scale bar: 20 μm) and (c) immunohistochemistry staining (; scale bar: 200 μm). AMPS: A. mellea polysaccharides.