Comparative Analysis of AGE and RAGE Levels in Human Somatic and Embryonic Stem Cells under H2O2-Induced Noncytotoxic Oxidative Stress Conditions
RAGE mRNA quantification by real-time PCR amplification of hES and somatic cells upon differentiation. (a) This study showed a decrease RAGE mRNA in adult neural, Hs27 and HUVEC compared to embryonic cells, 3 independent analyses per group. (b) Moreover, the qPCR analysis showed a decreased number of RAGE transcripts mean ± SD, 3 separate replicates. Statistically significant differences between groups are indicated as follows: , , and as established by one-way ANOVA and Tukey’s post hoc test.
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