Activation of the Nrf2-Keap 1 Pathway in Short-Term Iodide Excess in Thyroid in Rats

Figure 3

Effects of the iodide intake (NI, 10 HI, and 100 HI) on the changes of (a) Nrf2; (b) Keap 1; (c) Srx; and (d) Prx 3 expressions on Days 7, 14, and 28. Representative western blot and histograms of densitometric analyses normalized for the relative β-actin content. All data is presented as the mean ± SD ( for each group). Statistical analyses were performed by one-way analysis of variance (ANOVA) with the Least Significant Difference (LSD) test. versus the NI group on Days 7, 14, and 28, respectively. versus the 10 HI group on Days 7, 14, and 28, respectively. Experiments were repeated 3 times with similar results.

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