Research Article

Activation of the Nrf2-Keap 1 Pathway in Short-Term Iodide Excess in Thyroid in Rats

Table 1

Changes of the median urinary iodine concentration (μg/L) of Wistar rats following the intake of NI, 10 HI, and 100 HI on Days 7, 14, and 28 ( for each group). All data is presented as the median (range).

GroupThe median urinary iodine concentration (μg/L)
Day 7Day 14Day 28

NI321.2 (150.0–351.7)358.2 (300.2–373.8)333.0 (188.6–413.5)
10 HI3052.5 (1592.8–3798.0)3532.5 (1487.0–4056.0)2628.0 (1651.0–3404.5)
100 HI26489.2 (5856.6–42170.4)24461.0 (17607.5–29874.8)22663.2 (8342.5–29816.2)

Compared to the NI group ().
Compared to the 10 HI group ().