Rutin as a Mediator of Lipid Metabolism and Cellular Signaling Pathways Interactions in Fibroblasts Altered by UVA and UVB Radiation

Figure 4

The xanthine oxidase activity (a), NADPH oxidase activity (b), and superoxide anion generation (c) in fibroblasts after exposure to UVA [20 J/cm²], UVB radiation [200 mJ/cm²], and rutin [25 μM] treatment and pretreatment, expressed as a percentage of the control cells value. Mean values ± SD of five independent experiments are presented. Statistically significant differences versus control group, . Statistically significant differences versus group without rutin, . Statistically significant differences versus group without rutin pretreatment, .

(a)

(b)

(c)