Research Article

Rutin as a Mediator of Lipid Metabolism and Cellular Signaling Pathways Interactions in Fibroblasts Altered by UVA and UVB Radiation

Table 1

The activity of enzymatic (GSH-Px, GSSG-R, SOD, and TrxR) and the level of nonenzymatic (GSH, vitamin E, and Thx) antioxidants in fibroblasts after exposure to UVA [20 J/cm2], UVB radiation [200 mJ/cm2], and rutin [25 µM] treatment, expressed as a percentage of the control cells value.

ControlUVAUVB

GSH-PX activityWithout rutin
With rutin

GSSG-R activityWithout rutin
With rutin

SOD activityWithout rutin
With rutin

TrxR activityWithout rutin
With rutin

GSH levelWithout rutin
With rutin

Vitamin E levelWithout rutin
With rutin

Trx levelWithout rutin
With rutin

Mean values ± SD of five independent experiments are presented.
Statistically significant differences versus control group, .
Statistically significant differences versus group without rutin, .