Rutin as a Mediator of Lipid Metabolism and Cellular Signaling Pathways Interactions in Fibroblasts Altered by UVA and UVB Radiation

Table 2

The level of oxidative modifications products of DNA, lipids, and proteins in fibroblasts after exposure to UVA [20 J/cm²], UVB radiation [200 mJ/cm²], and rutin [25 µM] treatment and pretreatment, expressed as a percentage of the control cells value.

		Control	UVA	UVB
8-OHdG level	Without rutin
	With rutin
4-HNE level	Without rutin
	With rutin
MDA level	Without rutin
	With rutin
Iso-prostaglandin F2α level	Without rutin
	With rutin
4-HNE-protein adducts level	Without rutin
	With rutin
Carbonyl groups level	Without rutin
	With rutin
	With rutin pretreatment
Tryptophan level	Without rutin
	With rutin
Tyrosine level	Without rutin
	With rutin
3Cl-tyrosine level	Without rutin
	With rutin
3NO2-tyrosine level	Without rutin
	With rutin
Dityrosine level	Without rutin
	With rutin

Mean values ± SD of five independent experiments are presented.
Statistically significant differences versus control group, .
Statistically significant differences versus group without rutin, .
Statistically significant differences versus group without rutin pretreatment, .