Oxidative Medicine and Cellular Longevity / 2017 / Article / Fig 1

Research Article

Blockage of NOX2/MAPK/NF-κB Pathway Protects Photoreceptors against Glucose Deprivation-Induced Cell Death

Figure 1

Inhibition of NOX2 suppresses GD-induced oxidative stress. (a)–(f) Intracellular ROS was measured with DCFH-DA identified by green fluorescence. (a)–(d) 661W cells were cultured in normal medium (a) or glucose-free medium for 8 h (b), 16 h (c), and 24 h (d). (e)-(f) 661W cells were treated with 100 μM NSC (e) or 100 μM APO (f) during the course of GD for 16 h. Scale bar = 25 μm. (g) Fluorescence intensities were measured and relative fluorescence was statistically analyzed, scale bar = 25 μm. The results are presented as means ± SEM (, compared to the control group, ### compared to the vehicle group; one-way ANOVA and Bonferroni test).
(a)
(b)
(c)
(d)
(e)
(f)
(g)

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.