|
Accession | ID | Description | Gene | PANTHER family/subfamily | PANTHER protein class | PANTHER GO-slim molecular function | PANTHER GO-slim biological process | PANTHER GO-slim cellular component | Pathway |
|
P61158 | ARP3_ HUMAN | Actin-related protein 3 | ACTR3 | Actin-related protein 3 (PTHR11937:SF175) | Actin and actin-related protein(PC00085) | Structural constituent of cytoskeleton (GO:0005198) | Cytokinesis(GO:0009987); mitosis(GO:0000910); cellular component morphogenesis(GO:0007049); intracellular protein transport(GO:0007067); exocytosis(GO:0032502); endocytosis(GO:0009653); cellular component organization(GO:0032989) | Actin cytoskeleton(GO:0043226); intracellular(GO:0005856) | |
|
P02765 | FETUA_ HUMAN | Alpha-2-HS-glycoprotein | AHSG | Alpha-2-HS-glycoprotein (PTHR13814:SF6) | Extracellular matrix glycoprotein(PC00102); cysteine protease inhibitor(PC00100) | Cysteine-type peptidase activity(GO:0003824); protein binding (GO:0016787); cysteine-type endopeptidase inhibitor activity (GO:0008233) | Immune system process(GO:0002376); proteolysis(GO:0008152); mesoderm development(GO:0044238); skeletal system development(GO:0019538); regulation of catalytic activity (GO:0006508) | Extracellular region (GO:0005576); extracellular matrix (GO:0031012) | |
|
P38606 | VATA_ HUMAN | V-type proton ATPase catalytic subunit A | ATP6V1A | V-type proton atpase catalytic subunit A (PTHR15184:SF7) | ATP synthase(PC00227); anion channel (PC00068); ligand-gated ion channel (PC00002); ligand-gated ion channel (PC00133); DNA-binding protein (PC00049); hydrolase (PC00141) | Hydrolase activity (GO:0003824); receptor activity (GO:0016787); anion channel activity (GO:0004872); ligand-gated ion channel activity (GO:0005215); cation transmembrane transporter activity (GO:0022857); proton-transporting ATP synthase activity, rotational mechanism (GO:0005216); single-stranded DNA binding (GO:0005253) | Respiratory electron transport chain (GO:0008152); purine nucleobase metabolic process (GO:0006091); cation transport (GO:0022904) | Proton-transporting ATP synthase complex (GO:0032991); intracellular (GO:0043234) | |
|
P62158 | CALM_ HUMAN | Calmodulin | CALM1 | Calmodulin (PTHR23050:SF216) | Calmodulin (PC00060) | Calcium ion binding (GO:0005488); calmodulin binding (GO:0005509) | Cellular component movement (GO:0009987); cell cycle (GO:0006928); cell communication (GO:0007049) | | CCKR signaling map→CaM; B cell activation→calmodulin; heterotrimeric G-protein signaling pathway-rod outer segment phototransduction→ calmodulin; T cell activation→ calmodulin |
P48643 | TCPE_ HUMAN | T-complex protein 1 subunit epsilon | CCT5 | T-complex protein 1 subunit epsilon (PTHR11353:SF94) | Chaperonin (PC00072) | | Protein folding (GO:0008152); protein complex assembly (GO:0044238); protein complex biogenesis (GO:0019538) | | |
|
Q9UKY7 | CDV3_ HUMAN | Protein CDV3 homolog | CDV3 | Protein CDV3 homolog (PTHR16284:SF13) | | | | | |
|
P09497 | CLCB_ HUMAN | Clathrin light chain B | CLTB | Clathrin light chain B (PTHR10639:SF2) | Vesicle coat protein (PC00150) | | Intracellular protein transport (GO:0051179); receptor-mediated endocytosis (GO:0006810) | Vesicle coat (GO:0032991); cytoplasm (GO:0043234) | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha-mediated pathway→clathrin; heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha-mediated pathway→clathrin; Huntington disease→clathrin |
|
P20674 | COX5A_ HUMAN | Cytochrome C oxidase subunit 5A, mitochondrial | COX5A | Cytochrome C oxidase subunit 5A, mitochondrial (PTHR14200:SF11) | Oxidase(PC00176) | Oxidoreductase activity (GO:0003824) | Oxidative phosphorylation (GO:0008152); respiratory electron transport chain (GO:0006091) | | |
|
P07108 | ACBP_ HUMAN | Acyl-CoA-binding protein | DBI | Acyl-CoA-binding protein (PTHR23310:SF54) | Transfer/carrier protein (PC00219); enzyme modulator (PC00095) | Catalytic activity (GO:0003824); protein binding (GO:0005488); enzyme inhibitor activity (GO:0005515) | Lipid metabolic process (GO:0008152); lipid transport (GO:0044238); regulation of catalytic activity (GO:0006629) | | |
|
Q15075 | EEA1_ HUMAN | Early endosome antigen 1 | EEA1 | Early endosome antigen 1 (PTHR23164:SF6) | | | | | |
|
Q92538 | GBF1_ HUMAN | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 | GBF1 | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (PTHR10663:SF138) | Signaling molecule (PC00207); guanyl-nucleotide exchange factor (PC00095); cytoskeletal protein (PC00022) | GTPase activity (GO:0003824); pyrophosphatase activity (GO:0016787); nucleotide binding (GO:0003924); small GTPase regulator activity (GO:0016462); guanyl-nucleotide exchange factor activity (GO:0005488) | Phosphate-containing compound metabolic process (GO:0008152); nitrogen compound metabolic process (GO:0006796); catabolic process (GO:0006807); nucleobase-containing compound metabolic process (GO:0009056); cellular process (GO:0044238); transport (GO:0006139); regulation of biological process (GO:0009987); regulation of catalytic activity (GO:0051179) | Organelle (GO:0043226); intracellular(GO:0044464) | |
|
P78417 | GSTO1_ HUMAN | Glutathione S-transferase omega-1 | GSTO1 | Glutathione S-transferase omega-1 (PTHR11260:SF323) | Transferase (PC00220); signaling molecule (PC00207); reductase (PC00176); translation elongation factor (PC00198); epimerase/ racemase (PC00171); cytoskeletal protein (PC00031) | Oxidoreductase activity (GO:0003824); transferase activity (GO:0016491); racemase and epimerase activity (GO:0016740); structural constituent of cytoskeleton (GO:0016853); translation elongation factor activity (GO:0016854); translation elongation factor activity (GO:0005198); receptor binding (GO:0005200); translation elongation factor activity (GO:0005488) | Immune system process (GO:0002376); translation (GO:0008152); cell communication (GO:0044238); response to toxic substance (GO:0019538); regulation of translation (GO:0006412) | Cytoskeleton (GO:0043226); intracellular (GO:0005856) | |
|
P09211 | GSTP1_ HUMAN | Glutathione S-transferase P | GSTP1 | Glutathione S-transferase P (PTHR11571:SF141) | | | | | |
|
P51858 | HDGF_ HUMAN | Hepatoma-derived growth factor | HDGF | Hepatoma-derived growth factor (PTHR12550:SF41) | Transcription cofactor (PC00218); growth factor (PC00217) | Transcription cofactor activity (GO:0000988); sequence-specific DNA-binding transcription factor activity (GO:0000989); sequence-specific DNA-binding transcription factor activity (GO:0003712); growth factor activity (GO:0001071) | Immune system process (GO:0002376); transcription from RNA polymerase II promoter (GO:0008152); cell-cell signaling (GO:0044238); regulation of transcription from RNA polymerase II promoter (GO:0006139) | | |
|
O60814 | H2B1K_ HUMAN | Histone H2B type 1-K | HIST1H2BK | Histone H2B type 1-K (PTHR23428:SF23) | Histone (PC00171) | Nucleic acid binding (GO:0005488) | Nitrogen compound metabolic process (GO:0008152); DNA metabolic process (GO:0006807); cellular process (GO:0044238); chromatin organization (GO:0006139); chromatin assembly (GO:0006259); cellular component biogenesis (GO:0009987) | Protein DNA complex (GO:0032991); nucleus (GO:0032993); nuclear chromosome (GO:0043226); intracellular (GO:0005634) | |
|
P17096 | HMGA1_ HUMAN | High mobility group protein HMG-I/HMG-Y | HMGA1 | High mobility group protein HMG-I/HMG-Y (PTHR23341:SF1) | DNA-binding protein (PC00171) | Nucleic acid-binding transcription factor activity (GO:0001071); lyase activity (GO:0003824); DNA binding (GO:0016829) | Nitrogen compound metabolic process (GO:0008152); biosynthetic process (GO:0006807); DNA repair (GO:0009058); transcription, DNA-dependent (GO:0044238); cellular process (GO:0006139); response to stress (GO:0006259); regulation of nucleobase-containing compound metabolic process (GO:0006281) | Organelle (GO:0043226); intracellular (GO:0044464) | |
|
P52926 | HMGA2_ HUMAN | High mobility group protein HMGI-C | HMGA2 | High mobility group protein HMGI-C (PTHR23341:SF4) | DNA-binding protein (PC00171) | Nucleic acid-binding transcription factor activity (GO:0001071); lyase activity (GO:0003824); DNA binding (GO:0016829) | Nitrogen compound metabolic process (GO:0008152); biosynthetic process (GO:0006807); DNA repair (GO:0009058); transcription, DNA-dependent (GO:0044238); cellular process (GO:0006139); response to stress (GO:0006259); regulation of nucleobase-containing compound metabolic process 2(GO:0006281) | Organelle (GO:0043226); intracellular (GO:0044464) | |
|
P09429 | HMGB1_ HUMAN | High mobility group protein B1 | HMGB1 | High mobility group protein B1-related (PTHR13711:SF164) | HMG box transcription factor (PC00218); signaling molecule (PC00024); chromatin/ chromatin-binding protein (PC00207) | | | | p53 pathway→high mobility group protein 1 |
|
P05114 | HMGN1_ HUMAN | Nonhistone chromosomal protein HMG-14 | HMGN1 | Nonhistone chromosomal protein HMG-14 (PTHR23087:SF12) | Chromatin/ chromatin- binding protein (PC00171) | Nucleic acid binding (GO:0005488); chromatin binding (GO:0003676) | DNA replication (GO:0008152); transcription from RNA polymerase II promoter (GO:0044238); cell cycle (GO:0006139) | | |
|
P05204 | HMGN2_ HUMAN | Nonhistone chromosomal protein HMG-17 | HMGN2 | Nonhistone chromosomal protein HMG-17 (PTHR23087:SF13) | Chromatin/chromatin- binding protein (PC00171) | Nucleic acid binding (GO:0005488); chromatin binding (GO:0003676) | DNA replication (GO:0008152); transcription from RNA polymerase II promoter (GO:0044238); cell cycle (GO:0006139) | | |
|
P61604 | CH10_ HUMAN | 10 kDa heat shock protein, mitochondrial | HSPE1 | 10 kDa heat shock protein, mitochondrial (PTHR10772:SF16) | Chaperonin (PC00072) | | Protein metabolic process (GO:0008152) | | |
|
P50213 | IDH3A_ HUMAN | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | IDH3A | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (PTHR11835:SF34) | Dehydrogenase (PC00176) | Oxidoreductase activity (GO:0003824) | Generation of precursor metabolites and energy (GO:0008152); carbohydrate metabolic process (GO:0006091); tricarboxylic acid cycle (GO:0044238) | | Ascorbate degradation→ L-xylulose-5-phosphate- 3-epimerase; leucine biosynthesis→ 3-isopropylmalate dehydrogenase |
|
P01861 | IGHG4_ HUMAN | Ig gamma-4 chain C region | IGHG4 | IG gamma-1 chain c region-related (PTHR23266:SF83) | | | | | |
|
Q9GZP8 | IMUP_ HUMAN | Immortalization upregulated protein | IMUP | Immortalization upregulated protein (PTHR21830:SF0) | | | | | |
|
P04732 | MT1E_ HUMAN | Metallothionein-1E | MT1E | Metallothionein-1E (PTHR23299:SF2) | | | | | |
|
P13640 | MT1G_ HUMAN, MT1X_ HUMAN, MT2_ HUMAN | Metallothionein-1G, metallothionein-1X, metallothionein-2 | MT1G | Metallothionein-1G (PTHR23299:SF3) | | | | | |
|
P35749 | MYH11_ HUMAN | Myosin-11 | MYH11 | Myosin-11 (PTHR13140:SF335) | G-protein modulator (PC00095); actin-binding motor protein (PC00022); cell junction protein (PC00085) | Motor activity (GO:0003824); structural constituent of cytoskeleton (GO:0016787); protein binding (GO:0016462); enzyme regulator activity (GO:0003774) | Metabolic process (GO:0008152); cytokinesis (GO:0009987); cellular component movement (GO:0000910); mitosis (GO:0006928); cell communication (GO:0007049); muscle contraction (GO:0007067); sensory perception of sound (GO:0007154); sensory perception (GO:0032501); mesoderm development (GO:0044707); anatomical structure morphogenesis (GO:0003008); muscle organ development (GO:0006936); intracellular protein transport (GO:0007605); vesicle-mediated transport (GO:0050877); regulation of catalytic activity (GO:0007600); cellular component organization (GO:0032502) | Plasma membrane (GO:0016020); actin cytoskeleton (GO:0005886); intracellular (GO:0043226) | Inflammation mediated by chemokine and cytokine signaling pathway→myosin; nicotinic acetylcholine receptor signaling pathway→myosin; cytoskeletal regulation by Rho GTPase→myosin light chain |
|
P20929 | NEBU_ HUMAN | Nebulin | NEB | Nebulin (PTHR11039:SF37) | | | | | |
|
Q13442 | HAP28_ HUMAN | 28 kDa heat- and acid-stable phosphoprotein | PDAP1 | 28 kDa heat- and acid-stable phosphoprotein (PTHR22055:SF0) | | | | | |
|
P13667 | PDIA4_ HUMAN | Protein disulfide- isomerase A4 | PDIA4 | Protein disulfide-isomerase A4 (PTHR18929:SF110) | | Isomerase activity (GO:0003824) | Protein folding (GO:0008152); cellular process (GO:0044238); response to stress (GO:0019538) | Organelle (GO:0043226); cytoplasm (GO:0044464) | |
|
Q9UHV9 | PFD2_ HUMAN | Prefoldin subunit 2 | PFDN2 | PREFOLDIN SUBUNIT 2 (PTHR13303:SF0) | Chaperone (PC00072) | | protein folding (GO:0008152) | | |
|
O15212 | PFD6_ HUMAN | Prefoldin subunit 6 | PFDN6 | Prefoldin subunit 6 (PTHR21431:SF0) | | Protein binding (GO:0005488) | Protein complex assembly (GO:0008152); cellular process (GO:0044238); cellular component organization (GO:0019538); protein complex biogenesis (GO:0006461) | Protein complex (GO:0032991); cytosol (GO:0043234) | |
|
Q01813 | PFKAP_ HUMAN | ATP-dependent 6-phosphofructoki nase, platelet type | PFKP | 6-Phosphofructokinase type C (PTHR13697:SF5) | Carbohydrate kinase (PC00220); carbohydrate kinase (PC00137) | Carbohydrate kinase activity (GO:0003824) | Glycolysis (GO:0008152); glycolysis (GO:0006091) | | |
|
P13797 | PLST_ HUMAN | Plastin-3 | PLS3 | Plastin-3 (PTHR19961:SF32) | Nonmotor actin-binding protein (PC00085) | Structural constituent of cytoskeleton (GO:0005198); actin binding (GO:0005200) | Cellular process (GO:0009987); cellular component morphogenesis (GO:0032502); cellular component organization (GO:0009653) | Actin cytoskeleton (GO:0043226); intracellular (GO:0005856) | |
|
O75334 | LIPA2_ HUMAN | Liprin-alpha-2 | PPFIA2 | Liprin-alpha-2 (PTHR12587:SF6) | | | Cellular process (GO:0009987); cell adhesion (GO:0022610); ectoderm development (GO:0007155); nervous system development (GO:0032502) | | |
|
P30048 | PRDX3_ HUMAN | Thioredoxin- dependent peroxide reductase, mitochondrial | PRDX3 | Thioredoxin-dependent peroxide reductase, mitochondrial (PTHR10681:SF22) | Peroxidase (PC00176) | Oxidoreductase activity (GO:0003824); peroxidase activity (GO:0016491) | Metabolic process (GO:0008152) | | |
|
P49721 | PSB2_ HUMAN | Proteasome subunit beta type-2 | PSMB2 | Proteasome subunit beta type-2 (PTHR11599:SF6) | | | | | |
Q13200 | PSMD2_ HUMAN | 26S proteasome non-ATPase regulatory subunit 2 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 (PTHR10943:SF1) | Enzyme modulator (PC00095) | Catalytic activity (GO:0003824); protein binding (GO:0005488); enzyme regulator activity (GO:0005515) | Proteolysis (GO:0008152); cell cycle (GO:0044238); regulation of catalytic activity (GO:0019538) | | Ubiquitin proteasome pathway→26S proteasome; |
|
O00233 | PSMD9_ HUMAN | 26S proteasome non-ATPase regulatory subunit 9 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 (PTHR12651:SF1) | Enzyme modulator (PC00095) | | Protein complex assembly (GO:0008152); cellular component organization (GO:0044238); protein complex biogenesis (GO:0019538) | Protein complex (GO:0032991); organelle (GO:0043234); intracellular (GO:0043226) | Ubiquitin proteasome pathway→26S proteasome; |
|
P06454 | PTMA_ HUMAN | Prothymosin alpha [cleaved into: prothymosin alpha, N-terminally processed; thymosin alpha-1] | PTMA | Prothymosin alpha (PTHR22745:SF0) | | | Nucleobase-containing compound metabolic process (GO:0008152) | | |
|
P20962 | PTMS_ HUMAN | Parathymosin | PTMS | Parathymosin (PTHR22745:SF3) | | | Nucleobase-containing compound metabolic process (GO:0008152) | | |
|
P26373 | RL13_ HUMAN | 60S ribosomal protein L13 | RPL13 | 60S ribosomal protein L13 (PTHR11722:SF0) | Ribosomal protein (PC00171) | Structural constituent of ribosome (GO:0005198); nucleic acid binding (GO:0003735) | Translation (GO:0008152) | | |
|
P62277 | RS13_ HUMAN | 40S ribosomal protein S13 | RPS13 | 40S ribosomal protein S13 (PTHR11885:SF6) | Ribosomal protein (PC00171) | Structural constituent of ribosome (GO:0005198); nucleic acid binding (GO:0003735) | Protein metabolic process (GO:0008152) | | |
|
P62857 | RS28_ HUMAN | 40S ribosomal protein S28 | RPS28 | 40S ribosomal protein S28 (PTHR10769:SF4) | Ribosomal protein (PC00171) | Structural molecule activity (GO:0005198) | Cellular process (GO:0009987); RNA localization (GO:0051179); nucleobase-containing compound transport (GO:0006403); nuclear transport (GO:0006810); cellular component biogenesis (GO:0015931) | Ribosome (GO:0032991); organelle (GO:0030529); cytosol (GO:0005840) | |
|
Q8NC51 | PAIRB_ HUMAN | Plasminogen activator inhibitor 1 RNA-binding protein | SERBP1 | Plasminogen activator inhibitor 1 RNA-binding protein (PTHR12299:SF29) | RNA-binding protein (PC00171) | RNA binding (GO:0005488) | Primary metabolic process (GO:0008152) | | |
|
Q9H299 | SH3L3_ HUMAN | SH3 domain- binding glutamic acid-rich-like protein 3 | SH3BGRL3 | SH3 domain-binding glutamic acid-rich-like protein 3 (PTHR12232:SF3) | | | | | |
|
P11166 | GTR1_ HUMAN | Solute carrier family 2, facilitated glucose transporter member 1 | SLC2A1 | Solute carrier family 2, facilitated glucose transporter member 1 (PTHR23503:SF51) | | | | | Gonadotropin releasing hormone receptor pathway→Glut1; gonadotropin releasing hormone receptor pathway→Glut1; gonadotropin releasing hormone receptor pathway→Glut1 |
|
P22528 | SPR1B_ HUMAN | Cornifin-B | SPRR1B | Cornifin-B (PTHR23263:SF47) | | | | | |
|
Q9Y6N5 | SQRD_ HUMAN | Sulfide:quinone oxidoreductase, mitochondrial | SQRDL | Sulfide:quinone oxidoreductase, mitochondrial (PTHR10632:SF2) | | | | | |
|
Q16629 | SRSF7_ HUMAN | Serine/arginine- rich splicing factor 7 | SRSF7 | | | | | | |
|
P16949 | STMN1_ HUMAN | Stathmin | STMN1 | Stathmin (PTHR10104:SF5) | | Cytoskeletal protein binding (GO:0005488) | Cellular process (GO:0009987); single-multicellular organism process (GO:0032501); cell differentiation (GO:0044707); nervous system development (GO:0032502); regulation of biological process (GO:0030154); cytoskeleton organization (GO:0048731) | Intracellular (GO:0044464); cell projection (GO:0005622) | Cytoskeletal regulation by Rho GTPase→stathmin |
|
P61956 | SUMO2_ HUMAN | Small ubiquitin-related modifier 2 | SUMO2 | Small ubiquitin-related modifier 2-related (PTHR10562:SF11) | | | Cellular protein modification process (GO:0008152); cell cycle (GO:0044238) | | |
|
P63313 | TYB10_ HUMAN | Thymosin beta-10 | TMSB10 | Thymosin beta-10 (PTHR12021:SF10) | | | | | |
|
P62328 | TYB4_ HUMAN | Thymosin beta-4 | TMSB4X | Thymosin beta-4 (PTHR12021:SF13) | | | | | |
|
P67936 | TPM4_ HUMAN | Tropomyosin alpha-4 chain | TPM4 | Tropomyosin alpha-4 chain (PTHR19269:SF40) | Actin-binding motor protein (PC00085) | Motor activity (GO:0003824); structural constituent of cytoskeleton (GO:0016787) | Metabolic process (GO:0008152); cellular component movement (GO:0009987); muscle contraction (GO:0006928); ectoderm development (GO:0032501); mesoderm development (GO:0044707); cellular component morphogenesis (GO:0003008); nervous system development (GO:0006936); muscle organ development (GO:0032502); cellular component organization (GO:0007398) | Actin cytoskeleton (GO:0043226); intracellular (GO:0005856) | |
Q9C030 | TRIM6_ HUMAN | Tripartite motif-containing protein 6 | TRIM6 | Tripartite motif-containing protein 6 (PTHR24103:SF348) | | | | | |
|
Q13509 | TBB3_ HUMAN | Tubulin beta-3 chain | TUBB3 | Tubulin beta-3 chain (PTHR11588:SF43) | Tubulin (PC00085) | Structural constituent of cytoskeleton (GO:0005198) | Cell cycle (GO:0009987); anatomical structure morphogenesis (GO:0007049); intracellular protein transport (GO:0032502) | Protein complex (GO:0032991); intracellular (GO:0043234) | Huntington disease→beta-tubulin; Huntington disease→microtubule; cytoskeletal regulation by Rho GTPase→tubulin |
|
O75152 | ZC11A_ HUMAN | Zinc finger CCCH domain- containing protein 11A | ZC3H11A | Zinc finger CCCH domain-containing protein 11A (PTHR15725:SF2) | Nucleic acid binding (PC00171) | Nucleic acid binding (GO:0005488) | | | |
|