Anticataractogenesis and Antiretinopathy Effects of the Novel Protective Agent Containing the Combined Extract of Mango and Vietnamese Coriander in STZ-Diabetic Rats

Table 1

Opacity index of the lens of control and diabetic rats (DM) which received either vehicle or MPO at doses of 2, 10, and 50 mg/kg·BW for 10 weeks (). ^#,## value < .05 and .01, respectively, compared with control group and value < .05, .01, and .001, respectively, compared with diabetic rats which received vehicle (DM + vehicle).

Time duration	Opacity index of the lens (mean ± SEM)
	Control	DM + vehicle	DM + MPO (2 mg/kg·BW)	DM + MPO (10 mg/kg·BW)	DM + MPO (50 mg/kg·BW)
Baseline	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00
Week 1	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00
Week 2	0.00 ± 0.00	0.25 ± 0.08^#	0.10 ± 0.06	0.13 ± 0.06	0.21 ± 0.08
Week 3	0.00 ± 0.00	0.42 ± 0.12^#	0.50 ± 0.09	0.53 ± 0.09	0.54 ± 0.10
Week 4	0.00 ± 0.00	1.00 ± 0.12^##	0.67 ± 0.09	0.87 ± 0.06	0.71 ± 0.09
Week 5	0.00 ± 0.00	1.46 ± 0.12^##	0.87 ± 0.06	1.00 ± 0.00	0.86 ± 0.07
Week 6	0.00 ± 0.00	2.04 ± 0.18^##	1.23 ± 0.14	1.37 ± 0.11	1.39 ± 0.16
Week 7	0.08 ± 0.08	2.50 ± 0.17^##	1.70 ± 0.17	1.77 ± 0.13	1.71 ± 0.21
Week 8	0.17 ± 0.11	3.17 ± 0.20^##	2.37 ± 0.14	2.17 ± 0.17	2.57 ± 0.23
Week 9	0.42 ± 0.15	3.67 ± 0.10^##	3.03 ± 0.13	2.81 ± 0.21	3.04 ± 0.19
Week 10	0.42 ± 0.15	4.00 ± 0.00^##	3.64 ± 0.11	3.38 ± 0.16	3.61 ± 0.11