Anticataractogenesis and Antiretinopathy Effects of the Novel Protective Agent Containing the Combined Extract of Mango and Vietnamese Coriander in STZ-Diabetic Rats

Table 2

Comparison of aldose reductase, malondialdehyde (MDA), catalase (CAT), glutathione peroxidase (GPx), and superoxide dismutase (SOD) in lens of all groups. C: control group; DM + vehicle: diabetic rats (DM) which received vehicle; DM + MPO (2 mg/kg·BW): diabetic rats (DM) which received MPO at doses of 2 mg/kg·BW; DM + MPO (10 mg/kg·BW): diabetic rats (DM) which received MPO at doses of 10 mg/kg·BW; DM + MPO (50 mg/kg·BW): diabetic rats (DM) which received MPO at doses of 50 mg/kg·BW (). ^#,##,### value < .05, .01, and .001, respectively, compared with control group and value < .05, .01, and .001, respectively, compared with diabetic rats which received vehicle (DM + vehicle).

Group	MDA (U/mg protein)	CAT (U/mg protein)	GPx (U/mg protein)	SOD (U/mg protein)	AR (nmol/min/mg)
Control	0.52 ± 0.08	19.55 ± 0.59	1.01 ± 0.11	8.98 ± 0.34	0.005 ± 0.001
DM + vehicle	1.06 ± 0.10^###	13.04 ± 0.84^###	0.62 ± 0.04^##	6.83 ± 0.87^#	0.013 ± 0.004^##
DM + MPO (2 mg/kg·BW)	0.73 ± 0.03	17.91 ± 0.55	0.80 ± 0.10	8.06 ± 0.36	0.007 ± 0.001
DM + MPO (10 mg/kg·BW)	0.87 ± 0.05	17.69 ± 0.92	0.85 ± 0.01	7.28 ± 0.43	0.008 ± 0.001
DM + MPO (50 mg/kg·BW)	0.98 ± 0.05	16.61 ± 1.35	0.71 ± 0.04	6.10 ± 0.52	0.008 ± 0.001