Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model

Figure 4

Overrepresented biological process assigned according to Gene Ontology (GO) classification in the retinas of aged C3-deficient mice compared to WT mice. Groups of genes fulfilling criteria: adjusted value < 0.05, method = Benjamini, and minimum number of genes per group = 5, are presented in a graph, where bubble size indicates the number of genes represented in corresponding annotation and the condition of these genes in terms of their up- and downregulation.