Research Article

Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model

Figure 5

Gene set enrichment analysis (GSEA) of the retinas from aged C3-deficient mice compared to WT mice. Diagrams represent selected gene sets enriched in C3-deficient mice (secretory pathway, phototransduction, and neurological system process) and WT control animals (morphogenesis of an epithelium, immune response, and inflammatory response).