Sulforaphane Prevents Angiotensin II-Induced Testicular Cell Death via Activation of NRF2

Figure 1

Deletion of the Nrf2 gene completely abolished SFN protection against Ang II-induced decrease in testicular weight and spermatozoa count. (a) Testis weight to tibia length ratio was calculated after WT and Nrf2-null mice were killed. (b) Sperm density assessment was done by performing spermatozoa count. (c) H&E staining was conducted for observation of morphological change. Data are presented as means ± SD (). versus Ctrl; versus Ang II. versus WT mice treated with Ang II.

(a)

(b)

(c)