Sulforaphane Prevents Angiotensin II-Induced Testicular Cell Death via Activation of NRF2

Figure 2

SFN alleviated Ang II-induced testicular apoptotic cell death through the activation of NRF2. (a) TUNEL staining was performed to evaluate the effect of SFN on Ang II-induced testicular apoptotic cell death. Mitochondrial pathway was further evaluated by determining (b) the ratio of Bax to Bcl-2 and (c) the protein level of Caspase-3. For (b) and (c), data were normalised by respective Ctrl and presented as means ± SD (). versus Ctrl; versus Ang II; versus WT mice treated with Ang II.

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(b)

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