Metallothionein in Brain Disorders

Figure 4

Representative images of immunohistochemical study of MT in the brain (striatum) after MCAO. Control rats (a, c) and MCAO (b, d). (a, c) Neurons, astrocytes, and fibers with normal appearance. (b, d) Interstitial edema, altered neurons (N), and reactive astrocytes are observed after MCAO. Strong immunoreactivity to MT (brown color) was consistently detected in reactive astrocytes (↑) in treated animals. Magnification (a, b) 400x and (c, d) 1000x.

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