Antioxidant and Antifibrotic Effect of a Herbal Formulation In Vitro and in the Experimental Andropause via Nrf2/HO-1 Signaling Pathway

Figure 4

Immunoexpression of 3β-HSD (arrow) in Leydig cells of rat testis after treatment. ×400. (a) The normal control group (, normal control); (b) the androgen-deprived control group (, Androgen-dep. control); (c) the androgen-deprived 200 mg/kg group (, Androgen-dep. 200); (d) the androgen-deprived 400 mg/kg group (, Androgen-dep. 400); and (e) positive rate of 3β-HSD-immunoreactive cells. The difference was statistically significant ( and ). And the experiments were repeated for three times.

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