Antioxidant and Antifibrotic Effect of a Herbal Formulation In Vitro and in the Experimental Andropause via Nrf2/HO-1 Signaling Pathway
Table 1
Comparisons of parameters of the testicular health.
Testicular weight (g)
Epididymal weight (g)
Germinal cell layer thickness (μm)
Diameter of seminiferous tubules (μm)
Serum testosterone (ng/ml)
Normal control
1.62 ± 0.19
0.68 ± 0.03
73.22 ± 6.34
297.34 ± 4.33
2.48 ± 0.41
Androgen-dep. control
1.09 ± 0.06
0.40 ± 0.08
42.19 ± 2.69
251.16 ± 3.62
1.28 ± 0.34
Androgen-dep. 200
1.15 ± 0.17
0.45 ± 0.06
52.46 ± 3.92
271.31 ± 1.36
1.32 ± 0.52
Androgen-dep. 400
1.30 ± 0.05
0.59 ± 0.01
69.86 ± 7.10
280.14 ± 8.32
1.72 ± 0.13
Data show the mean ± s.d. analysis of variance test. Significant statistical difference () compared with the normal control group. Significant statistical difference () compared with the androgen-deprived control group.
