NADPH Oxidase 2 Regulates NLRP3 Inflammasome Activation in the Brain after Traumatic Brain Injury

Figure 11

Additional Western blots for IL-1β. Blot showing cleaved IL-1β product in different set of WT ctrl, WT 4d TBI, and KO 4d TBI mice and an additional APO 4d TBI mouse from those depicted in Figure 10. Densitometry quantification represents samples in this set of blots relative to respective loading controls. Inhibition of NOX2 via either knockout or apocynin reduces protein expression of cleaved IL-1β. Data presented as fold change relative to WT ctrl mice. ( WT ctrl versus WT TBI; ^# WT TBI versus APO TBI; ^### WT TBI versus KO TBI).