Baicalin Ameliorates Experimental Liver Cholestasis in Mice by Modulation of Oxidative Stress, Inflammation, and NRF2 Transcription Factor

Figure 1

Baicalin significantly attenuated BDL-induced liver fibrosis in mice. (a) Chemical structure of baicalin. (b) BDL-induced liver fibrosis as measured by picrosirius red staining. The images were quantified in a blinded manner by ImageJ software (c). BDL resulted in severe liver fibrosis which was attenuated by baicalin treatment. Results are mean ± S.E.M. for each group. versus control and ^# versus BDL. (d) Representative images for highlighting necrosis area in BDL and BDL samples pretreated with baicalin.

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