Clinical Study

Low-Level Laser Irradiation Exerts Antiaggregative Effect on Human Platelets Independently on the Nitric Oxide Metabolism and Release of Platelet Activation Markers

Table 1

Comparison of platelet aggregation, nitric oxide bioavailability markers, and platelet activation markers between groups.

Laser-treated group (after LLLT)
(19.8 J/cm2)
Control group (without LLLT)
(0 J/cm2)
value

ADP aggregation [AU]66.8 ± 22.272.9 ± 22.7
TRAP aggregation [AU]91.5 ± 21.9105.0 ± 23.5
Collagen aggregation [AU]57.7 ± 19.664.7 ± 22.3
L-arginine [μmol/l]37.6 ± 10.438.1 ± 11.5ns
ADMA [μmol/l]0.40 ± 0.070.42 ± 0.06ns
SDMA [μmol/l]0.23 ± 0.080.24 ± 0.07ns
sP-selectin [ng/ml]26.9 ± 9.825.58 ± 9.8ns
PF4 [ng/ml]541.9 ± 521.5519.6 ± 501.2ns

TRAP: thrombin receptor activating peptide; ADMA: asymmetric dimethylarginine; SDMA: symmetric dimethylarginine; PF4: platelet factor 4.