Comparison of Effects of Different Statins on Contrast-Induced Acute Kidney Injury in Rats: Histopathological and Biochemical Findings

Table 1

Effects of statins on renal function, in rats with contrast-induced acute kidney injury (CI-AKI).

	Control ()	CI-AKI ()	CI-AKI + RUS ()	CI-AKI + SSTN ()	CI-AKI + ATO ()
SCr at baseline (μmol/L)
SCr at 24 h after CM injection (μmol/L)
Change in SCr above baseline (%)
AKI rate	0% (0/9)	88.89% (8/9)	44.44% (4/9)	66.67% (6/9)	22.22% (2/9)

Results are expressed as mean ± SEM. versus control group, versus CI-AKI group, versus CI-AKI group, versus SCr at baseline, and versus SCr at baseline.
ATO: atorvastatin; CM: contrast media; RUS: rosuvastatin; SCr: serum creatinine; SSTN: simvastatin.