Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice

Figure 3

Effect of SkQ1 on the maturation of granulation tissue in diabetic mice. Representative images of the (a) Mallory’s trichrome-stained and (b) ɑ-SMA- and (c) CD-31-immunostained granulation tissue at the 7th day of wound healing. (d) Percentage of the area containing α-SMA-positive cytoplasm (areal density). (e) Percentage of the area containing microvessels (vessel density). Data are presented as mean ± SEM; for SkQ1-treated versus untreated diabetic mice. ^‡ for the untreated diabetic mice versus nondiabetic mice.

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