Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice

Figure 6

Effect of SkQ1 on the cell motility in the scratch-wound assay under high-glucose conditions. Migration of human subcutaneous fibroblasts in a scratch-wound assay (48 h after wounding). (a) Representative images. (b) Percentage of the wound area occupied with migrated cells. “Control”—control medium (25 mM glucose); “mannitol”—control medium (50 mM mannitol); “glucose”—high-glucose medium (50 mM glucose); “SkQ1 + glucose”—high-glucose medium (20 nM SkQ1). Data are presented as mean ± SEM; ^‡ for the high-glucose versus control medium. for SkQ1-treated high-glucose versus high-glucose medium.

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