Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis

Figure 5

NOx concentration in the blood plasma. All forms of NO (NOx) in plasma were measured at BL (0 h), 6, 24, 48, and 72 h post-CLP. At BL: control , SkQ1 , MitoTEMPO ; at 6 h: control , SkQ1 , MitoTEMPO ; at 24 h: control , SkQ1 , MitoTEMPO ; at 48 h: control , SkQ1 , MitoTEMPO ; at 72 h: control , SkQ1 , MitoTEMPO . Data points shown as mean ± SEM. The inset depicts scatter plot of all groups at 24 h post-CLP time point.