Lung-Protective Ventilation Strategies for Relief from Ventilator-Associated Lung Injury in Patients Undergoing Craniotomy: A Bicenter Randomized, Parallel, and Controlled Trial

Table 1

Patient characteristics and intraoperative data.

Characteristics	Treatment groups
	CV group; ()	PV group; ()	value
Age, years	47 (10)	48 (10)	0.782
Sex, M/F	14/13	15/13	0.898
Weight, kg	68 (9)	66 (9)	0.346
Height, cm	167 (8)	168 (7)	0.765
ASA class I/II	10/17	9/19	0.703
Smoking habit	4 (15%)	5 (18%)	NS
Procedures
Meningioma	12 (44%)	13 (46%)	NS
Glioma	7 (26%)	8 (29%)	NS
Intracranial aneurysm	8 (30%)	7 (25%)	NS
Duration of mechanical ventilation, min	400.8 (43.8)	408.3 (52.3)	0.549
Duration of surgery, min	347.2 (48.0)	348.5 (56.7)	0.928

Values are given as mean ± standard deviation or number of patients (%). CV group, conventional mechanical ventilation with 12 mL/kg tidal volume (V_T) and 0 cm H₂O positive end-expiratory pressure (PEEP); PV group, protective lung ventilation with 6 mL/kg V_T and 10 cm H₂O PEEP. ASA class, American Society Anesthesiologists’ physical status.