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Oxidative Medicine and Cellular Longevity
Volume 2017, Article ID 6568501, 9 pages
https://doi.org/10.1155/2017/6568501
Research Article

Change of the State of the Natural Antioxidant Barrier of a Body and Psychological Parameters in Patients Aged above 60

1Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland
2Institute of Physical Education, Kazimierz Wielki University in Bydgoszcz, Bydgoszcz, Poland
3Student Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland
4Department of Physiotherapy, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland
5Neurocognitive Laboratory, Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University, Toruń, Poland
6Department of Biochemistry, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland

Correspondence should be addressed to Emilia Mikołajewska; lp.pw@akswejalokim.e

Received 22 July 2017; Revised 30 September 2017; Accepted 8 October 2017; Published 19 December 2017

Academic Editor: Janusz Gebicki

Copyright © 2017 Katarzyna Porzych et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. The goal of this study is to assess the natural antioxidant barrier of the organism and selected psychological aspects of the aging process in patients above 60 years old. Methods. The study included a total of 52 patients aged above 60 (mean age 67 ± 3.4) and 32 healthy subjects (mean age 22 ± 3.4) as a control group. All patients underwent psychological assessment using Test of Attentional Performance version 2.3 (TAP 2.3, four subtests: alertness, cross-modal integration, neglect with central task, and working memory) and biochemical analysis of venous blood concerning values of the selected parameters of oxidative stress (HT, GSH, GPXOS, GPXRBC, GRRBC1, SODRBC1, MDARBC1, NO2/NO3, and CP). Results. Disorders of attention were observed mainly in elderly people, but an assumption that elderly people have developed more efficient ways of working memory use than younger people may be true. Results showed the reduced effectiveness of the body’s natural antioxidant barrier in elderly people. Moderate positive and negative correlations among parameters of oxidative stress and psychological parameters were observed in the control group. Discussion. Intensification of the attention deficits and oxidative stress may be observed as one of the pathogenic factors of age-dependent diseases.