Spondias purpurea L. (Anacardiaceae): Antioxidant and Antiulcer Activities of the Leaf Hexane Extract

Figure 9

Histological analysis of the gastric mucosa of animals submitted to the induction of ulcer with ethanol. Animals were pretreated with 1% Tween 80 aqueous solution: injured control (a), lansoprazole (b), and SpHE 12.5 mg/kg (c), 25 mg/kg (d), and 50 mg/kg (e). Observed in (a): disorganization of the columnar simple epithelium in the gastric pits (enlarged detail, arrowhead) and gastric glands (arrows), congestion of the blood capillaries (enlarged detail, asterisk), and necrosis of the gastric mucosa cells (arrowhead); in (b): columnar simple epithelium in the gastric pits (enlarged detail) and well-preserved gastric glands (arrows); in (c): poorly preserved gastric mucosa, exfoliations of the columnar simple epithelium, and necrosis of the superficial epithelium (enlarged detail); and in (d) and (e): well-preserved gastric mucosa (enlarged detail).

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(b)

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(e)