Echinacoside Alleviates UVB Irradiation-Mediated Skin Damage via Inhibition of Oxidative Stress, DNA Damage, and Apoptosis

Figure 7

Echinacoside decreased CPD levels in BALB/c mice and HaCaT cells exposed to UVB. (a) Paraffin-embedded sections of the mouse skin were used to immunohistological staining with CPDs. The red arrow shows the epidermis thickness of BALB/c mice, and the black arrow shows CPD-positive cell. (b) Cells were pretreated with echinacoside (25, 50, and 100 μM) prior to UVB exposure. After 24 h, the cells were collected to quantify CPD production using ELISA analysis. Data are presented as means ± SD (). ^## versus control group, versus UVB group.

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