Research Article
Pathway-Driven Approaches of Interaction between Oxidative Balance and Genetic Polymorphism on Metabolic Syndrome
Table 4
Association of the OBS with metabolic syndrome by weighing method
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| | OBS | Number of cases (control) | OR (95% CI) | | trend |
| | OBS-equal weight (AUC = 0.823) | | | Quantile 1 | 547 (1522) | 1 | | <0.01 | | Quantile 2 | 314 (855) | 0.94 (0.78–1.15) | 0.56 | | Quantile 3 | 510 (1685) | 0.81 (0.68–0.97) | 0.02 | | Quantile 4 | 186 (724) | 0.65 (0.51–0.82) | <0.01 | | OBS-equal weight (AUC = 0.823) | | | Quantile 1 | 353 (1351) | 1 | | <0.01 | | Quantile 2 | 205 (774) | 0.91 (0.72–1.14) | 0.40 | | Quantile 3 | 328 (1513) | 0.79 (0.64–0.97) | 0.02 | | Quantile 4 | 118 (644) | 0.60 (0.45–0.81) | <0.01 | | OBS-beta coefficient (AUC = 0.824) | | | Quantile 1 | 378 (1204) | 1 | | <0.01 | | Quantile 2 | 397 (1161) | 0.65 (0.52–0.81) | <0.01 | | Quantile 3 | 431 (1209) | 0.67 (0.49–0.90) | <0.01 | | Quantile 4 | 355 (1212) | 0.56 (0.76–0.41) | <0.01 | | OBS-beta coefficient (AUC = 0.829) | | | Quantile 1 | 239 (1089) | 1 | | <0.01 | | Quantile 2 | 272 (1047) | 0.66 (0.50–0.87) | <0.01 | | Quantile 3 | 376 (1050) | 0.66 (0.47–0.91) | 0.01 | | Quantile 4 | 218 (1107) | 0.56 (0.38–0.82) | <0.01 | | OBS-PCA (AUC = 0.824) | | | Quantile 1 | 375 (1203) | 1 (reference) | | <0.01 | | Quantile 2 | 389 (1174) | 0.64 (0.51–0.79) | <0.01 | | Quantile 3 | 419 (1189) | 0.68 (0.50–0.92) | 0.01 | | Quantile 4 | 372 (1216) | 0.55 (0.40–0.75) | <0.01 | | OBS-PCA (AUC = 0.828) | | | Quantile 1 | 233 (1087) | 1 | | <0.01 | | Quantile 2 | 251 (1068) | 0.71 (0.55–0.92) | <0.01 | | Quantile 3 | 292 (1037) | 0.66 (0.46–0.96) | 0.03 | | Quantile 4 | 228 (1098) | 0.62 (0.43–0.91) | 0.01 |
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Adjusting for age, sex, area, and BMI. Excluded patients with type 2 diabetes; .
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