Oxidative Medicine and Cellular Longevity / 2017 / Article / Fig 2

Research Article

Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis

Figure 2

Effect of edaravone on alteplase-induced thrombolysis under flow conditions in whole blood. (a) Typical still videomicroscopy images of thrombogenesis and thrombolysis over 27 to 28 min in samples exposed to alteplase or edaravone-alteplase. The asterisk (white area) indicates thrombi. (b) Flow-pressure curves in the control, edaravone, alteplase, and edaravone-alteplase groups (). The arrow indicates an alteplase nonresponder, and the arrowhead indicates incomplete responders. (c) AUC30 in the alteplase and edaravone-alteplase groups. AUC30: area under the curve at 30 min.

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