Elucidation of Molecular Mechanisms of Streptozotocin-Induced Oxidative Stress, Apoptosis, and Mitochondrial Dysfunction in Rin-5F Pancreatic β-Cells

Figure 7

STZ-induced alterations in CYP activities. CYP 1A1 and CYP 1A2 activities were measured in Rin-5F cells treated with different doses of STZ at different time intervals using the respective substrates as described in the Materials and Methods. Results are expressed as mean ± SEM of three experiments. Asterisks indicate significant difference (, ) relative to the untreated control cells.

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