Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-κB-Dependent Autophagy

Figure 7

Immunohistochemical analysis of NF-κB expression in pancreas tissues of rats. C3, C6, and C12, the healthy rats were treated with 25 mg/kg 0.9% saline solution for 3, 6, and 12 h, respectively. M3, M6, and M12, the SAP model were treated with 25 mg/kg 0.9% saline solution for 3, 6, and 12 h, respectively. P3, P6, and P12, the SAP models were treated with 25 mg/kg picroside II for 3, 6, and 12 h, respectively. Data were presented as means ± SD from five independent experiments. versus the control group; ^# versus the picroside II-treated group (25 mg/kg).