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Oxidative Medicine and Cellular Longevity
Volume 2017, Article ID 7126872, 13 pages
https://doi.org/10.1155/2017/7126872
Research Article

Xylopine Induces Oxidative Stress and Causes G2/M Phase Arrest, Triggering Caspase-Mediated Apoptosis by p53-Independent Pathway in HCT116 Cells

1Gonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, Brazil
2Department of Chemistry, Federal University of Sergipe, São Cristóvão, SE, Brazil
3Center of Biotechnology and Cell Therapy, Hospital São Rafael, 41253-190 Salvador, BA, Brazil
4Department of Chemistry, Federal University of Amazonas, Manaus, AM, Brazil

Correspondence should be addressed to Daniel Pereira Bezerra; moc.liamg@arrezebpleinad

Received 6 August 2017; Revised 12 September 2017; Accepted 20 September 2017; Published 6 December 2017

Academic Editor: Spencer Gibson

Copyright © 2017 Luciano de Souza Santos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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