Edible Bird’s Nest Prevents Menopause-Related Memory and Cognitive Decline in Rats via Increased Hippocampal Sirtuin-1 Expression

Table 1

Body weights and serum estrogen levels of ovariectomized rats after 12 weeks.

	Body weight (g) before treatment	Body weight (g) end point	Total weight gain (g)	Total food intake (g)	Serum estrogen (pg/ml)
Control	221.5 ± 33.5	227.5 ± 6.0	6.0	1109.3 ± 40.6	151.1 ± 8
Sham	217.8 ± 44.0	224.6 ± 6.8	6.8	1065.4 ± 23.8	156.7 ± 13
OVX	230 ± 29.7	283.1 ± 23.1^b	53.1^b	1276.2 ± 56.9^b	35.6 ± 0.9^b
Estrogen	236 ± 33.3	239 ± 3.0^a	3.0^a	976.8 ± 47.5^a,b	169.8 ± 11.4^a
EBN (high)	213.1 ± 41.8	214.5 ± 1.4^a	1.4^a	1023.5 ± 23.3^a	150.4 ± 7.4^a
EBN (middle)	228.1 ± 53.9	242.8 ± 14.6^a	14.6^a	1088.6 ± 40.4^a	147.8 ± 8.7^a
EBN (low)	216 ± 31.5	242.6 ± 26.7	26.7^a	1111.5 ± 37.6^a	143.3 ± 13.4^a

Control: standard rat chow; sham: surgically opened but not ovariectomized and fed with standard rat chow; OVX: ovariectomized with semipurified pellet; estrogen: ovariectomized and fed with standard rat chow and 0.2 mg/kg body weight of estrogen; EBN high, medium, and low: ovariectomized and fed with standard rat chow and 1.2, 0.6, and 0.3 g/kg body weight of edible bird’s nest/day, respectively. Values are mean ± SD, . ^aMean value was significantly different from that of the OVX group (); ^bmean value was significantly different from that of the sham group ().