Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells

Table 1

Kinetic constants of the TDG and SMUG1 proteins for the excision of thymine mispaired with 8BrG.

Type of protein	Km (nM)	Kcat (min^−1)	Kcat/Km (min^−1·μM^−1)
TDG	0.72	0.042	58.5
SMUG1	2.63	0.011	4.2