Antioxidant and Anti-Inflammatory Effects of Shungite against Ultraviolet B Irradiation-Induced Skin Damage in Hairless Mice
Antioxidant enzyme activities of serum and skin lysates in shungite-treated mice groups: glutathione peroxidase (GPx), superoxide dismutase (SOD), and myeloperoxidase (MPO) levels. Shown are the antioxidant biological enzyme activities such GPX in serum (a) and skin lysates (d), SOD in serum (b) and skin lysates (e), and MPO in serum (c) and skin lysates (f) of shungite-treated UVB-induced mice. Control groups include non-UVB-irradiated group (NC), UVB-irradiated only group (UV), UVB + fullerene-treated positive control group (PC), and UVB + olive oil-treated group (OIL), while experimental groups include UVB + mineral-rich shungite-treated group (MRS) and mineral-less shungite-treated group (MLS). Statistical analysis was carried out using analysis of variance (ANOVA) followed by subsequent multiple comparison test (Tukey’s multiple comparisons test) using GraphPad Prism version 5.0. Data were expressed as mean ± SD, , , versus each treatment groups.
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