Uncoupling Protein 2: A Key Player and a Potential Therapeutic Target in Vascular Diseases

Figure 2

Schematic representation of UCP2 gene upregulation. Schematic representation of the pharmacological, vegetable, and humoral factors known to positively modulate UCP2 gene transcription. As a consequence of the UCP2 protein overexpression, several beneficial effects are observed in the vascular system with a significant reduction of the vascular disease occurrence.