Plasma DNA Mediate Autonomic Dysfunctions and White Matter Injuries in Patients with Parkinson’s Disease

Table 3

Correlations among diffusion tensor abnormalities, oxidative stress, and cardiovascular autonomic parameters.

WM tract	Correlation of clinical variable ( value)
	Baroreflex sensitivity (BRS)	Nuclear DNA	Mitochondrial DNA
Left parietal WM
FA	0.280/0.158	−0.286/0.148	−0.296/0.134
MD	−0.272/0.410	0.165/0.410	0.096/0.633
AD	−0.104/0.604	−0.026/0.896	−0.097/0.629
RD	−0.315/0.109	0.241/0.226	0.188/0.347
Left middle cerebellar peduncle
FA	0.370/0.058
MD	−0.202/0.312	0.125/0.534	0.248/0.211
AD	−0.007/0.971	−0.118/0.557	0.034/0.865
RD	−0.311/0.114	0.280/0.157	0.369/0.058
Left cingulum
FA	0.199/0.319	−0.305/0.122	0.054/0.789
MD			0.207/0.299
AD	−0.377/0.052		0.314/0.111
RD			0.110/0.583

Correlations among diffusion tensor abnormalities, oxidative stress biomarkers, and cardiovascular autonomic parameters were performed by partial correlation after controlling for age and sex.
, uncorrected.
with a Bonferroni correction, accounting for multiple region of interest comparisons.
FA, fractional anisotropy; AD, axial diffusivity; RD, radial diffusivity; BRS, baroreflex sensitivity; WM, white matter.